Melphalan Hydrochloride

Phenylalaninemustardhydrochloride, Alaninenitrogenmustardhydrochloride, Melphalan Hydrochloride


Generic

CAS No

3223-07-2



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Melphalan is a phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter-strand cross-linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non-dividing tumor cells.

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